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L-Azidohomoalanine hydrochloride

CAS No. 942518-29-8

L-Azidohomoalanine hydrochloride( —— )

Catalog No. M35251 CAS No. 942518-29-8

L-Azidohomoalanine hydrochloride (H-L-Aha-OH hydrochloride) is an alkyl chain-based PROTAC linker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 36 Get Quote
25MG 56 Get Quote
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Biological Information

  • Product Name
    L-Azidohomoalanine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    L-Azidohomoalanine hydrochloride (H-L-Aha-OH hydrochloride) is an alkyl chain-based PROTAC linker.
  • Description
    L-Azidohomoalanine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-Azidohomoalanine (hydrochloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    PROTAC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    942518-29-8
  • Formula Weight
    180.59
  • Molecular Formula
    C4H9ClN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 125 mg/mL (692.18 mM; Ultrasonic)
  • SMILES
    Cl.N[C@@H](CCN=[N+]=[N-])C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.?
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